Introduction of a single amino acid substitution (Gln979 to Ile) into the 130- and 180-kDa proteins of tomato mosaic tobamovirus (ToMV) rendered the mutant virtually unable to replicate in tomato cells while it replicated perfectly in tobacco cells. The mechanism of this change in host specificity is discussed.

Vol. 10, No. 8
November 1997
ISSN:0894-0282
e-ISSN:1943-7706

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Article History
- Issue Date: 25 Jan 2008
- Published: 19 Feb 2007
- Accepted: 16 Jul 1997
Pages: 1015-1018

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© 1997 The American Phytopathological Society
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  - Virology

A Single Amino Acid Substitution in the Virus-Encoded Replicase of Tomato Mosaic Tobamovirus Alters Host Specificity

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